SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb5e019eb01e8add763101306d8edfdaccf90d9e782bc2cc8175166b4bb4560' 
  AND token = '+aS5cF8B24Gf18j3Saviwa75szvVbPgmE9BIGlIZhaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}