SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d05bd6b3daaba3833ea4cc729972360732f7df49984e819d70b87c25021d575' 
  AND token = '3N8BeoJpGuyFfNlYlsY39p406JXdEk89yPI//u92CLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}