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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22f51de1419e0ed6186c48ba3de451facce7f0cb9dac2bb234da40ee7b474f8' 
  AND token = 'TwSjt0xJB8f4zZRPdx1vpUbErWaFITFOncrFw3Yp9Gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}