SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34f1c8026731a635aaf6635a0909a60813db5301999990749c3598ea01f4a4dc' 
  AND token = 'drEbA0JUHLJ9Dxd0U4rjNG43yST/SI7N5y3zqTH0ODM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}