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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2172ea85bf85923488b2f9a01d1abb5e21a61b593754133748abdbc0f09ff4e4' 
  AND token = 'q0dzCrEeb7JmSGTa8VH6CYZTw+CV//VcK857I5CQVdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}