SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '259eafe5e26f41ab7978a7f24cb998bb52897b479f998e9b748a2474676a4e75' 
  AND token = 'jkHOgeLjiFUY8o8GdH1aP7iUMqx9AfN/6vrbToBVcgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}