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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f74293e9af3484b902b80aa0eef435569503852fc0cb10eba90fa67380ef3e3' 
  AND token = 'GIYxbTi+Jro7lObm8Y/XJjxtn5LIPTuiehx3rpW2Khc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}