SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc052f2f756b78146cc5bd04679a53c94999af5d6b8029acf3e4cf2e8300605' 
  AND token = 'nSBEk9cIXNolD57zEgXQa5H4kJiN359cHLOm6i6fkhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}