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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ab77cc44495d27c20afe276f8ff5f409134fc78f341ca5e8e342b160dc6b9a2' 
  AND token = 'Zp3xyNFcHoH1XnCVDIu0zMMFfd9vcORtQV5efWhwfPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}