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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cdbfee177048822d4ba1577d488aed3d0b6f84edd1184669787e052f2dcde7c' 
  AND token = '1ZEn6WM0uq5pSznMHMhn4E+UaA3ERQ+D9VU9URL0aWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}