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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0cf9502c3827ff135c2f263fde8ff51965efc3005693a668df517d09ad9180c' 
  AND token = 'd3/5KvWsn6orPxaQcN+K9LF2aTp6GjaE7Gf2y0cuwi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}