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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe5a6f94ff6d45f5203644ada2eddd20a1774d0497b85fb3610b2f353e8b401' 
  AND token = '+6zKh7Rr04e2Dyf33wMwbC8BwoPTqfOuTXmwGo80J3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}