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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16dbc6df74afcb52ff7a7272d12a3f4c2132f042819f9366090b130ef51ae441' 
  AND token = 'TYzsudrZd0pcJ9V0QT0a9vpJMQXnGQazBQLrkZgU3uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}