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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc478dd113131e149c69a42603f866021d1f3e58fec2bcd15be1754e07423881' 
  AND token = 'H8o2jdeEzcvaSvbeurNO0nwO3Qt5v+SYGbaZEXMn828=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}