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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db4152d14e7c7d5e998b1ebd414ab82211a5717012a679ed654c507901a0a90f' 
  AND token = 'gtB1FWEMGNG5zkYCKAwr+JuiJLncx+RjQRo8uWdwAi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}