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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d650f1b9e9da013f67271a9918f965937addf34b8d0bdb2c54c740c7a4c190' 
  AND token = 'ZakUNFEquH6XN2u9amZj4lKPboTP5pNydYrAvzoeo1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}