SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0aaaaec87c9ebe201d2058739410d0263d18ab8c28e6c8b63b6422246ece84' 
  AND token = 'MPtYArKD2tss16PKFXFrNFQiUufWw5hiLmOQrAOTlW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}