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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f860918ad131133a2472ce324f0b933f0902f99458b4b0f6667674e4379932' 
  AND token = 'YKkhULFo4Vmiwhn5l7nqWWEbywboQlfBkhdweQxa1R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}