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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5f4201a93aa7a175cb37b2e28f127202b7d712c0a311b59dbb502a525d5fcd6' 
  AND token = 'QQivthp1EEVK+1Cwx1qSxsuW9RCXniO0gBCR3xe+wcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}