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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214979302250a440026b1bf1b29bbd97e755b9ef6b238e2ce724c2ab1e7d1807' 
  AND token = '4CRNV7BkfojfJR+/XfY66zWLJPO1zdfwULjvRAOupeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}