SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b49c9bcf2b69a600067b3092b76c6259ec509c3009a498ec3f29d4b71b61798' 
  AND token = 'sepnfp/QtN9s+2PnNIiwsym46+hTpvWN+5aIijaEDy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}