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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e654c83919b7e6d2d896f161b65a297cdb71c2e62a10e4c4619fc4cc1f10c09' 
  AND token = 'WqaGB2/CxqOy0jO1nCAzpkbqs3VUAxiOCiOHco9vbzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}