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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3acc617d89ed8c33992a2dd7e2450ea26f00c95e1adb7a957636f04b4cd4c9' 
  AND token = 'PJcTX1+1BjPt2pMQ/I6k6lzFImLNMnj3OksjyzqEYns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}