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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22f22eb8209a1711704859199f7f6b8120ca725940687de14bc3909ea505a33' 
  AND token = '1f+DyANCqWgLnyd35Jk+hpu6Sql5sZnerlWwj03QKTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}