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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8af06ea8a83da88d29680c4563d6225447ce19ed0ee0365effbd1d576830493' 
  AND token = 'fbWnVXA28+vNmOhuPv/9a0I4xHEVjvujj/nFI9V8blk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}