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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8d642d1fbf0b7905c612a83b830409f5e16d9290be99cbb0db7c644ef4cba1' 
  AND token = 'v67wsUdWvLCvW5IondeMmLKqRrZ9mXD2u/IB9cqC+UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}