SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36956b22c8782f3bb47016d40c9163f8ae3e2b406e0f59646ee641ec6d3651b' 
  AND token = 'rxmTYcVMEdX9dm1WCIZl2yalH0xwgzhLbmOWdKhPYYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}