SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fb68538e914b227b6c6ae6699ba85d6f256285890cb548ddbc757fd0cb6209' 
  AND token = 'fZaEYKR1lHTxqkELLbIyXOQl0DSlRsPKeB6scqdfSLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}