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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecfd09e6707375aed7233ecf65c172c2180889df1d2d572d7bd1118de19d603a' 
  AND token = 'AYZVOfE/vITTTfoH8w6Hs2b5QLWnWhHUl8Rn5QrG+QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}