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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89204e7882d16a173617109b57dd5b3b7f8b210adf64fe830f1583777232c3a0' 
  AND token = 'r1tcfC6pfA93EHTUL+oAr9zH9YjpSIl5pMb3TyS4lfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}