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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1444b86c6b51649ccbd39717b4eff11e9fea238b766e350386f20a455cc21b' 
  AND token = 'U74+SeCDR8+ZRgV3d6iZZS8gNkrazjcdxk6hQNi9QKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}