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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '258f02ca17008e10dbf7b8bde3243ef181db93e29face2ed24ae2f9652a7325f' 
  AND token = '+SrTIdKDArBwpYkTJnTnO9WWTkdh0ZwAhlZ7OqRfCoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}