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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b79cc36a8d276568e924ec9ce62431a2bdadc8063b8f61b19c0853f5f7a9fe11' 
  AND token = 'weU2Jir68EleVe5ySTuDEqmcOEhVz6vCXhku5YiXQKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}