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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1b2dcba1bb6aa9447915a839f4800de48654b1cb5a7ad0f29e5e4068a88a8a' 
  AND token = 'YIpB0jHZU2zNoS0MJS2MA8hLXOCCh0fXhslR/HPeuRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}