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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '868459ef5fade6b9821fa6f3338cc8d99b602c5485187aa06dc6a64c94868aa3' 
  AND token = 'sM8E0BGPymiJ8/rou8Ww1Exkw1b4wMDaQRtFaTJMWvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}