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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '572f01d9609ad54f499f01eec61cea945412c6f849956672025355b909fc5fe2' 
  AND token = 'XM0/i+01rkJ98wDdYtPsu6qPL/4UhoBBqDHgbGG1YwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}