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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a450ebfea5a2d247a5ada9adc7b488f1c9edacf6f990ec7f4cf54720071d55d5' 
  AND token = 'krhOJAN8puRAqFfC7cKX0K1vAYvmVf0XL+bAYYfzoRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}