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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e874c87d88650dab6bfc518a207d34028cede43a794e68c3ee0b3e7636fc523' 
  AND token = 'vVitBM+YtelWtLndUqEl4/pIQmxdJHor9CFTUYRa0ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}