SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed4b81df3ed94feef7433300944e9e23cf4516d627cf280f0e2e0b09a7082bc' 
  AND token = 'JL2gfXuAbEWGuJUIJWeGZncT+iLGm7Odo4QQQVfx7gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}