SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de6643f15082626b2478839e4ad2ee3faba42dd5b7b426a48a57ab9860effb6' 
  AND token = 'tnWATRjIh9oCOmbN35P2Qe18Ja3aNxZm/Kz9hCeJMhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}