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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18246e8f1c57eefe15e65cbbc675c1ecb3c34aa5da2ece4c821b5c3bf72afc89' 
  AND token = 'xYhf4vZ0ixz9evjSccYpVZLGIARcNdAgjK9W4raeTUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}