SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee2aaf04ccbe54ad6453aa388ea213f7b00821bcd4628ec110622d75653d163' 
  AND token = 'pdSoneNWtNd5UHx8krS9LWas9xQ/Jxkmo/sVdUU/XIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}