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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2968804c58be03d627c0b559ec760f85147be0adbc41fdfc9c95232015c2344' 
  AND token = 'wJxDV75nTBB0AqwPbZQw0pdO3EsAuzM5E8q0BheloLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}