SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b30e78bb77bff91cbcd417de292be7cc738e146d0d41bed0f1afe6e166df0ec' 
  AND token = '1qMTDadlfipd8nSIGkuAUaltQEyrXDDa9xB2/p21jzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}