SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8519a7e0245e05ed448e529e83dc25132384ea37c4e1755561dcdbe03c5e0b1' 
  AND token = 'vlVJZMsIvXU8O/wSo3UTfNJHLCsqGg70aeUL+kbu7lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}