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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4752f4e2bf678c5b5227b67950aa42d83d4a918c17d31e10da5cf78599131beb' 
  AND token = 'CrDoEQbwbCn7AByz7gM8aPbhzK2stqNBuhhg02Ws8r8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}