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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b567e6dd31aed41cc47b8c6cdf52b66d66250b689c717bd2fb8e3f3dd8764504' 
  AND token = 'KCMG8Eujyo3Xnmc0knHsC0mFmuxsRymIyQ7FUxwPZiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}