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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecaf4486441b6644b32448288d33a6912a240c07deb5c7576a46d0dcba269f2' 
  AND token = '2DQHrSzRoc2PmL0enkrlo1Eaf1En9OUctKgmbl+1zHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}