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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee845401e629e0c0ea9d00847ed2e5e3d3c5734e7d8d4b97dddf7b22581e30c1' 
  AND token = 'lE+F2P2wwYgA5i8KEvUnKYTKGGXyBdqhG+SuFriKHpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}