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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbf3e006211a6de489c676a35480d7750e4231819b1491fa8094034a65f293f8' 
  AND token = 'kM1k0b4t0TKso5IHi5D5HpdD7FXYYeZ1RALUMLG1Npk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}